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Islet cell transplantation print that page


Islets are usually infused into the patient's liver ,. [ 1 ] The patient's body, however, will treat the infused islets just as it would any other introduction of foreign tissue: the immune system will attack the islets as it would a viral infection, leading to the risk of transplant rejection

Insulin print that page


status is also used as a control signal to other body systems (such as amino acid uptake by body cells ). In addition, it has several other anabolic effects throughout the body. When control of insulin levels fails, diabetes mellitus will result. As a consequence, insulin is used medically

Beta cell print that page


Beta cells make and release insulin , a hormone that controls the level of glucose in the blood. There is a baseline level of glucose maintained by the liver, but the beta cells can respond quickly to spikes in blood glucose by releasing stored insulin while simultaneously producing more

Paul Langerhans print that pageTimeline of Paul Langerhans


Contributions to the microscopic anatomy of the pancreas ”, in which he refers to islands of clear cells throughout the gland, staining differently than the surrounding tissue. He noticed that these areas were more richly innervated, but he could not suggest a function, except for the

Langerhans cell histiocytosis print that page


characterized by an abnormal proliferation of histiocytes (an archaic term for activated dendritic cells and macrophages ). These diseases are related to other forms of abnormal proliferation of white blood cells , such as leukemias and lymphomas . The disease has gone by several names

Islets of Langerhans print that page


The islets of Langerhans are the regions of the pancreas that contain its endocrine (i.e., hormone-producing) cells . Discovered in 1869 by German pathological anatomist Paul Langerhans at the age of 22, [ 1 ] the islets of Langerhans constitute approximately 1 to 2% of the mass of

Langerhans cell print that page


The Langerhans cell is named after Paul Langerhans , a German physician and anatomist , who discovered the cells at the age of 21 while he was a medical student . [ 4 ] Because of their dendritic nature, he mistakenly identified the cells as part of the nervous system . [ 5 ] [ edit

Insulin resistance print that page

Insulin resistance in muscle and fat cells reduces glucose uptake (and also local storage of glucose as glycogen and triglycerides , respectively), whereas insulin resistance in liver cells results in reduced glycogen synthesis and storage and a failure to suppress glucose production and | 2011/7/15 3:45:29

Diabetes mellitus print that page


juvenile diabetes.) Type 2 diabetes : results from insulin resistance , a condition in which cells fail to use insulin properly, sometimes combined with an absolute insulin deficiency. (Formerly referred to as non-insulin-dependent diabetes mellitus, NIDDM for short, and adult-onset

Diabetes management print that page


requiring management is the glucose cycle, whereby glucose in the bloodstream is made available to cells in the body, a process dependent upon the twin cycles of glucose entering the bloodstream, and insulin allowing appropriate uptake into the cells of the body. Both aspects can require